C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/38 (2006.01) A61K 39/255 (2006.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01) C12N 7/01 (2006.01) C12N 7/02 (2006.01) C12N 15/86 (2006.01) C12N 15/869 (2006.01)
Patent
CA 2234423
The present invention relates to the use of continuous mammalian cell lines for the production of non-recombinant and recombinant Marek's Disease Virus, the production of genetically engineered Marek's Disease Virus and Marek's Disease Virus vectors, continuous mammalian cell lines infected with Marek's Disease Virus, Marek's Disease Virus vaccines produced using Marek's Disease Virus obtained using such processes and methods for protecting animals, such as avians, against disease by Marek's Disease Virus and/or other pathogens. Particularly, the mammalian cell lines capable of infection or transfection with MDV are feline kidney cell lines.
La présente invention concerne l'utilisation de lignées cellulaires mammaliennes continues pour la production du virus non recombinant et recombinant de la maladie de Marek, la production d'un virus génétiquement modifié de la maladie de Marek et de vecteurs du virus de la maladie de Marek, les lignées cellulaires mammaliennes continues infectées par le virus de la maladie de Marek, les vaccins contre le virus de la maladie de Marek produits à l'aide du virus de la maladie de Marek obtenu à l'aide de ces méthodes, et les procédés destinés à protéger des animaux, comme les poulets, contre la maladie causé par le virus de la maladie de Marek ou d'autres pathogènes. Plus précisément, les lignées cellulaires mammaliennes capables d'infection ou de transfection avec le MDV sont des lignées cellulaires hépatiques félines.
Brown Tracy Michelle
Calvert Jay Gregory
Deichert Michael Clayton
May Stephen Wayne
Mulkey Kent Michael
Pfizer Products Inc.
Smart & Biggar
LandOfFree
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