Processes for preparing...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 231/08 (2006.01) C07C 235/00 (2006.01)

Patent

CA 2528933

The present invention provides a process for the preparation of a compound of formula I [Chemical formula should be inserted here. Please see paper copy] in which a compound of formula II [Chemical formula should be inserted here. Please see paper copy] in which R is H or OR represents a protecting group for a carboxylic hydroxy group is reacted with a compound of formula III C6H13X wherein X is a leaving group, in the presence of a base in the presence of an inert solvent at a temperature in the range -25~C to 150~C and optionally, when OR represents a protecting group, removal of the protecting group.

La présente invention concerne un procédé de préparation d'un composé de formule I, dans lequel un composé de formule II, dans laquelle R représente H ou OR représente un groupe protecteur d'un groupe hydroxycarboxylique, est mis à réagir avec un composé de formule III, X représentant un groupe partant, en présence d'une base, en présence d'un solvant inerte à une température comprise entre -25 ·C et 150 ·C, avec, éventuellement, élimination du groupe protecteur lorsque OR représente un groupe protecteur.?¿

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