Processes for synthesizing 1-(2-ethylbutyl) cyclohexane...

Details Processes for synthesizing 1-(2-ethylbutyl) cyclohexane... Processes for synthesizing 1-(2-ethylbutyl) cyclohexane...

C - Chemistry, Metallurgy

07

C

C07C 253/30 (2006.01) C07C 255/46 (2006.01)

Patent

CA 2723088

Processes are provided for synthesizing substituted cyclohexane carbonitriles, particularly 1-(2-ethylbutyl)cyclohexane carbonitrile. Such processes comprise deprotonizing cyclohexane carbonitrile with chloro magnesium N,N-diisopropylamide and alkylating the deprotonated cyclohexane carbonitrile in the presence of 2-(ethylbutyl) bromide to produce 1-(2-ethyl-butyl)cyclohexane carbonitrile.

L'invention concerne des procédés de synthèse de cyclohexane carbonitriles substitués, en particulier le 1-(2-éthylbutyl)cyclohexane carbonitrile. Ces procédés comprennent la déprotonation du cyclohexane carbonitrile avec du chloromagnésium N,N-diisopropylamide et l'alkylation du cyclohexane carbonitrile déprotoné en présence de bromure de 2-(éthylbutyle) afin de produire du 1-(2-éthylbutyl)cyclohexane carbonitrile.

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