Processes for the manufacture of rosuvastatin and intermediates

C - Chemistry – Metallurgy – 07 – D

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C07D 239/42 (2006.01) C07D 239/30 (2006.01) C07D 239/36 (2006.01)

Patent

CA 2614281

A process for the manufacture of a compound of formula (V), useful for making rosuvastatin, by a stereoselective aldol reaction is described. Novel intermediates and processes to make them are also described.

L'invention concerne un procédé de préparation d'un composé de formule (V), utile pour la production de rosuvastatine, par l'intermédiaire d'une réaction aldolique stéréosélective. L'invention concerne également des nouveaux intermédiaires et des procédés de production de ceux-ci.

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