Processes for the preparation of 1-[2-benzimidazol-1-yl)...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) C07D 215/38 (2006.01) C07D 305/06 (2006.01)

Patent

CA 2529032

The present invention relates to a process for preparing a compound of the formula (I) or a pharmaceutically acceptable salt, prodrug, hydrate or solvate thereof, wherein R', R2, R3 and R4 are as defined herein. The compound of formula (I) is useful in the treatment of abnormal cell growth, such as cancer, in mammals.

L'invention porte sur un procédé permettant de préparer un composé représenté par la formule (I) et un sel, un promédicament, un hydrate ou un solvate pharmaceutiquement acceptable de ce composé, dans laquelle R', R<2>, R<3> et R<4> sont tels que définis dans le descriptif. Le composé de la formule (I) est particulièrement utile dans le traitement de la croissance cellulaire anormale, telle que le cancer, chez les mammifères.

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