Processes for the preparation of carbapenem-type...

Details Processes for the preparation of carbapenem-type... Processes for the preparation of carbapenem-type...

C - Chemistry, Metallurgy

07

D

C07D 495/08 (2006.01) A61K 31/407 (2006.01) A61P 31/04 (2006.01) C07D 477/06 (2006.01) C07D 477/20 (2006.01)

Patent

CA 2429071

A process for producing either a carbapenem-type antibacterial (4) having a 1- alkylpyrrolidine structure or a salt thereof, the process being shown by the following reaction formula; a compound represented by the formula (1) or a salt thereof which are useful intermediates therefor; and a process for producing the compound or salt. (1) .fwdarw. (4). In the formula, R1 represents C1-3 alkyl, and R2 and R3 each independently represents hydrogen, etc.

L'invention concerne un procédé de production soit d'un antibactérien (4) de type carbapenem présentant une structure 1-alkylpyrrolodine, soit d'un sel de celui-ci, ce procédé étant représenté par la formule de réaction suivante: (1)}(4); un composé représenté par la formule (1) ou un sel de celui-ci utilisé comme intermédiaire; et enfin, un procédé de production du composé/sel. Dans cette formule, R<1> représente C1-3 alkyle, et R<2> et R<3> représentent individuellement hydrogène, etc..

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