C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/7.06, 530/5.
C07K 14/665 (2006.01) C07K 5/107 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1156221
ABSTRACT OF THE DISCLOSURE: Process for the preparation of new biologically active peptides. These compounds correspond to the following general formula (I): Image (I) X-Tyr-A-Phe-B-C-W wherein X is a hydrogen atom or an N-terminal protective group; Y is a hydrogen atom or a group protecting the tyrosine hydroxyl- phenol group; A is a D-amino acid residue; B is a neutral L-amino acid residue; C is present or absent; when present it is a re- sidue of an amino acid or of a di- or tri-peptide; W is OH, OR, NH2, NHR, NR2, NHNHR'. As medications, they act upon the central nervous system as analgesics, antipsychotics and agents for use in neuro-endocrinology.
360511
Castiglione Roberto de
Faoro Fiorenzo
Perseo Giuseppe
Piani Silvano
Santangelo Francesco
Farmitalia Carlo Erba S.p.a.
George H. Riches And Associates
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