Processes for the preparation of s-(-)-amlodipine

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 211/90 (2006.01)

Patent

CA 2525699

The present invention provides a process for the preparation of S-(-)- amlodipine from (R,S)-amlodipine in industrial-scale using L-(+)-tartaric acid, which is much cheaper than D-(-)-tartaric acid.

La présente invention concerne un procédé de préparation de of S-(-)-amlodipine à partir de (R,S)-amlodipine à l'échelon industriel au moyen d'acide tartrique L-(+), lequel est bien meilleur marché que l'acide tartrique D-(-).

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