C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/90 (2006.01)
Patent
CA 2525699
The present invention provides a process for the preparation of S-(-)- amlodipine from (R,S)-amlodipine in industrial-scale using L-(+)-tartaric acid, which is much cheaper than D-(-)-tartaric acid.
La présente invention concerne un procédé de préparation de of S-(-)-amlodipine à partir de (R,S)-amlodipine à l'échelon industriel au moyen d'acide tartrique L-(+), lequel est bien meilleur marché que l'acide tartrique D-(-).
Chung You-Sup
Ha Mun-Choun
Hanlim Pharmaceutical Co. Ltd.
Ridout & Maybee Llp
LandOfFree
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