C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 489/12 (2006.01)
Patent
CA 2738628
The present invention is generally directed to a process for the preparation of a ketomorphinan comprising maintaining a ketone group as unprotected and performing reductive amination using a hydrogen source and a catalyst.
La présente invention concerne, de façon générale, un procédé de préparation d'un cétomorphinane comprenant les étapes consistant à maintenir un groupe cétone non protégé et à procéder à une amination réductrice en utilisant une source d'hydrogène et un catalyseur.
Cantrell Gary L.
Grote Christopher W.
Hudson Edmund C.
Teramura Douglas
Thomasson Catherine E.
Mallinckrodt Inc.
Osler Hoskin & Harcourt Llp
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