Processing method of lactonization in the preparation of...

Details Processing method of lactonization in the preparation of... Processing method of lactonization in the preparation of...

C - Chemistry, Metallurgy

07

D

C07D 309/30 (2006.01)

Patent

CA 2413235

The present invention relates to a processing method for preparing lovastatin and simvastatin which comprises the steps of (1) performing lactonization of mevinic acid and its homologous compounds in the presence of a mixed organic solvent without an acid catalyst through nitrogen sweep; and (2) making crystals. In the process of the present invention, lovastatin and simvastatin highly purified can be produced in a high yield and especially, heterodimers formed as a by-product can be reduced remarkably. Therefore, the processing method of the present invention can be convenient and economical.

Affiliated with

Also associated with

Rating

Processing method of lactonization in the preparation of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Processing method of lactonization in the preparation of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Processing method of lactonization in the preparation of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1773069