Processing of chitosan and chitosan derivatives

Details Processing of chitosan and chitosan derivatives Processing of chitosan and chitosan derivatives

C - Chemistry, Metallurgy

08

L

C08L 5/08 (2006.01) A61K 9/00 (2006.01) A61K 47/36 (2006.01) C08B 37/08 (2006.01)

Patent

CA 2622342

An article containing N-acylchitosan is manufactured by a process comprising the steps of providing a mixture containing chitosan and/or N-acylchitosan, and extruding the mixture to form an N-acylchitosan hydrogel. Alternatively, the process comprising the steps of providing a chitosan and/or N-acylchitosan hydrogel, and extruding the hydrogel. An article with a memorized shape is formed by fixing the N-acylchitosan hydrogel in a desired shape, and at least partially drying the fixed hydrogel. A patient is treated by injecting the N- acylchitosan hydrogel.

L'invention concerne un article à base de N-acylchitosane fabriqué selon un procédé consistant à obtenir un mélange contenant du chitosane et/ou N-acylchitosane, et à extruder le mélange pour former un hydrogel à base de N-acylchitosane. En variante, le procédé consiste à obtenir un hydrogel de chitosane et/ou N-acylchitosane, et à extruder l'hydrogel. Un article de forme mémorisée est obtenu par fixation de l'hydrogel à base de N-acylchitosane sous une forme désirée, et par séchage au moins partiel de l'hydrogel fixé. Un patient est traité par injection de l'hydrogel à base de N-acylchitosane.

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