C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 41/00 (2006.01) A61K 31/565 (2006.01) A61P 5/28 (2006.01) A61P 5/32 (2006.01) A61P 15/00 (2006.01) A61P 19/10 (2006.01)
Patent
CA 2629587
The invention relates to a prodrugs of 9.alpha.-substituted estratrienes of general formula (I), wherein the Z group is linked to a steroid, (I). The invention also relates to a methods for the production thereof, pharmaceutical compositions which contain said compounds, and to the use thereof. Said inventive compounds of general formula (I) do not bond with the oestrogen receptor alpha and/ or beta but they bond with carboanhydrases and inhibitors of said enzymes.
L'invention concerne des promédicaments d'estratriènes à substitution 9.alpha. de formule (I), dans lesquels le groupe Z est lié au stéroïde, (I). La présente invention porte également sur des procédés pour les réaliser, sur des compositions pharmaceutiques contenant ces composés et sur leur utilisation. Les composés de l'invention de formule (I) ne se lient pas au récepteur d'oestrogène alpha et/ou bêta, mais ils se lient à des carboanhydrases et inhibent ces enzymes.
Kosemund Dirk
Mueller Gerd
Wyrwa Ralf
Bayer Schering Pharma Aktiengesellschaft
Marks & Clerk
LandOfFree
Prodrug er.beta.-selective substances, methods for the... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Prodrug er.beta.-selective substances, methods for the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prodrug er.beta.-selective substances, methods for the... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1451369