C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/04 (2006.01) A61K 31/5383 (2006.01) A61K 31/675 (2006.01) A61P 37/00 (2006.01) C07F 9/6561 (2006.01)
Patent
CA 2673137
The present disclosure provides prodrugs of biologically active 2,4- pyrimidinediamine compounds, salts and hydrates of the prodrugs, compositions. comprising the prodrugs, intermediates and methods for synthesizing the prodrugs and methods of using the prodrugs in a variety of applications. In particular the claims relate to salts of the phosphate ester of the following structure:
La présente invention concerne des promédicaments de composés de 2,4-pyrimidinediamine biologiquement actifs, des sels et hydrates des promédicaments, des compositions comprenant ces promédicaments, des intermédiaires et procédés pour la synthèse de ces médicaments, et des procédés d'utilisation de ces promédicaments dans diverses applications.
Bhamidipati Somasekhar
Masuda Esteban
Singh Rajinder
Sun Thomas
Riches Mckenzie & Herbert Llp
Rigel Pharmaceuticals Inc.
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