Prodrugs of an inhibitor of hiv protease

Details Prodrugs of an inhibitor of hiv protease Prodrugs of an inhibitor of hiv protease

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 213/38 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2174649

Prodrugs of formula (I) are useful in the inhibition of HIV protease, the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition in- gredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

Bioprécurseurs de formule (I) s'avérant utiles dans l'inhibition de la protéase du VIH, dans le traitement des infections dues au VIH et dans le traitement du SIDA, soit sous forme de sels pharmacocompatibles, soit comme ingrédients de compositions pharmaceutiques, en combinaison ou non avec d'autres antiviraux, immunomodulateurs antibiotiques ou vaccins. Sont également décrites des méthodes de traitement du SIDA et des méthodes de prévention ou de traitement des infections dues au VIH.

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