Prodrugs of antihypercholesterolemic compounds

Details Prodrugs of antihypercholesterolemic compounds Prodrugs of antihypercholesterolemic compounds

C - Chemistry, Metallurgy

07

C

167/233, 167/246

C07C 235/34 (2006.01) A61K 31/215 (2006.01) A61K 31/22 (2006.01) C07C 233/45 (2006.01) C07D 233/64 (2006.01)

Patent

CA 1302425

4013S/1211A 17327 TITLE OF THE INVENTION PRODRUGS OF ANTIHYPERCHOLESTEROLEMIC COMPOUNDS ABSTRACT OF THE DISCLOSURE Prodrugs of 3-hydroxy-3-methylglutaryl- coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formula (I): Image (I) the amido ester moiety of which is in the L-configuration, and pharmaceutically acceptable salts thereof are disclosed.

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