C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 63/00 (2006.01) A61K 31/56 (2006.01) A61P 31/18 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2418479
A composition and method of preventing or inhibiting tumor growth and, more particularly, of treating a malignant tumor, using prodrugs of plant-derived compounds and derivatives is disclosed. In the method, a composition containing betulinic acid or a betulinic acid derivative is administered in a prodrug form to release betulinic acid or a betulinic acid derivative in vivo at the tumor site.
L'invention concerne une composition et un procédé permettant d'empêcher ou d'inhiber la croissance de tumeurs et, plus particulièrement, de traiter une tumeur maligne, grâce à des promédicaments de composés dérivés de plantes et de leurs dérivés. Dans le procédé de l'invention, une composition contenant de l'acide bétulinique ou un dérivé de l'acide bétulinique est administrée sous une forme de promédicament afin de libérer l'acide bétulinique ou un dérivé de l'acide bétulinique in vivo à l'emplacement de la tumeur.
Goldsmith Miriam Elaine
Kosmeder Jerome W. II
Pezzuto John M.
Xu Ze-Qi
Zhou Nian En
Advanced Life Sciences Inc.
Smart & Biggar
The Board Of Trustees Of The University Of Illinois
LandOfFree
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