Prodrugs of pharmaceuticals with improved bioavailability

Details Prodrugs of pharmaceuticals with improved bioavailability Prodrugs of pharmaceuticals with improved bioavailability

C - Chemistry, Metallurgy

07

F

C07F 9/6561 (2006.01) A61K 9/127 (2006.01) A61K 31/665 (2006.01) A61K 31/675 (2006.01) A61K 31/70 (2006.01) A61K 38/02 (2006.01) A61K 47/48 (2006.01) C07D 473/00 (2006.01) C07F 9/09 (2006.01) C07F 9/10 (2006.01) C07F 9/40 (2006.01) C07F 9/655 (2006.01) C07F 15/00 (2006.01) C07H 15/22 (2006.01) C07H 15/252 (2006.01) C07H 19/10 (2006.01) C07H 19/20 (2006.01) C07H 21/00 (2006.01) C07K 2/00 (2006.01)

Patent

CA 2223989

Lipid prodrugs of pharmaceutical agents and their analogs that have increased anticancer, anti-viral, anti-inflammatory, anti--proliferative activity over the parent drug, and methods for making lipid prodrugs. Compositions comprising lipid prodrugs for treating disease and methods for treating disease which involve using the compositions.

L'invention concerne des promédicaments lipidiques de substances pharmaceutiques et leurs analogues présentant une activité anticancéreuse, antivirale, anti-inflammatoire et anti-proliférative améliorée par rapport au médicament mère. L'invention concerne également des procédés de préparation de promédicaments lipidiques, des compositions thérapeutiques qui contiennent ces promédicaments lipidiques et des procédés de traitement de maladies au moyen de ces compositions.

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