Prodrugs of phosphonates

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 9/6561 (2006.01) A61K 31/675 (2006.01) C07F 9/6512 (2006.01) C07F 9/6571 (2006.01) C07F 9/6574 (2006.01) C07F 9/6584 (2006.01)

Patent

CA 2051239

There are disclosed novel oral prodrugs of phosphonate nucleotide analogs which are hydrolyzable under physiological conditions to yield compounds which are useful as antiviral agents, especially as agents effective against RNA and DNA viruses. They may also find use as antitumor agents.

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