Prodrugs of substituted 1,3-dioxanes and their uses

Details Prodrugs of substituted 1,3-dioxanes and their uses Prodrugs of substituted 1,3-dioxanes and their uses

C - Chemistry, Metallurgy

07

D

C07D 319/06 (2006.01) A61K 31/357 (2006.01)

Patent

CA 2676444

The present invention relates to prodrugs of compounds containing 1,3-dioxane moiety, pharmaceutical compositions thereof, and the use of the compounds and compositions for the modulation of thromboxane A2 or a peroxisome proliferator-activated receptor. The prodrugs of the compounds, analogs, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions can be used in the treatment and prevention of cancer.

La présente invention concerne des promédicaments de composés contenant une fraction 1,3-dioxane, des compositions pharmaceutiques de ceux-ci et l'utilisation des composés et compositions pour la modulation de thromboxane A2 ou d'un récepteur activé par proliférateur de peroxysome. Les promédicaments des composés, des analogues et des sels pharmaceutiquement acceptables de ceux-ci, et des compositions pharmaceutiques peuvent être utilisées dans le traitement et la prévention du cancer.

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