Product comprising a c4bp core protein and a monomeric...

Details Product comprising a c4bp core protein and a monomeric... Product comprising a c4bp core protein and a monomeric...

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 39/385 (2006.01) A61K 39/395 (2006.01) A61K 39/42 (2006.01) A61K 48/00 (2006.01) A61P 31/16 (2006.01) A61P 33/06 (2006.01) C07K 16/10 (2006.01) C07K 16/20 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/70 (2006.01) C12N 15/79 (2006.01)

Patent

CA 2535517

The invention provides a product which comprises a C4bp core protein and a monomeric antigen, desirably in the form of a fusion protein. Monomeric antigens include malarial and influenza antigens. The C4bp core protein provides for assembly of multimeric complexes of the monomeric antigen, or mixtures thereof. The complexes are useful as vaccines.

L'invention concerne un produit qui comprend une protéine C4bp du noyau et un antigène monomère, de préférence sous forme d'une protéine de fusion. Les antigènes monomères incluent les antigènes du paludisme et de la grippe. La protéine C4bp du noyau permet d'assembler des complexes multimères de l'antigène monomère ou de leurs mélanges. Les complexes sont utiles comme vaccins.

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