Product for inhibition of attachment of h. influenzae to...

Details Product for inhibition of attachment of h. influenzae to... Product for inhibition of attachment of h. influenzae to...

A - Human Necessities

61

K

A61K 38/17 (2006.01) A23C 9/20 (2006.01) A23L 1/305 (2006.01)

Patent

CA 2234680

A product is provided for inhibiting the attachment of H. influenzae to human cells, such as pharyngeal cells, by contacting the bacilli with phosphorylated recombinant human .beta.-casein that have at least 3 phosphate groups. The product containing phosphorylated recombinant human .beta.-casein may be a liquid enteral nutritional product such as infant formula. The enteral nutritional product may be used for the prevention and treatment of otitis media in infants. The phosphorylated recombinant human .beta.-casein may also be administered as a throat spray or used in nose drops or a spray.

La présente invention concerne un produit servant à inhiber la fixation de H. influenzae sur des cellules humaines, telles que les cellules du pharynx, par la mise en contact des bacilles avec de la caséine .beta. humaine recombinante phosphorylée ayant au moins trois groupes phosphate. Le produit contenant cette caséine peut être un produit nutritionnel entéral tel qu'un aliment lacté pour nourrissons. Ledit produit peut être utilisé pour prévenir et traiter l'otite moyenne du nourrisson. La caséine mentionnée peut aussi s'administrer sous forme d'aérosol pour la gorge ou être utilisée sous forme de gouttes nasales ou d'aérosol.

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