Product for the prophylaxis, diagnosis and therapy of...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/00 (2006.01) A61K 31/295 (2006.01) A61K 33/26 (2006.01) A61K 49/00 (2006.01) C12N 1/38 (2006.01)

Patent

CA 2042613

The product is manufactured by heating together a physiologically acceptable salt, or salts, of iron (Fe) and a lipid, or lipids. It is for topical cutaneous application as a prophylactic, diagnostic aid and/or remedy during the latent or clinical stage of systemic lupus erythematosus, vasculitis, sarcoidosis, amyloidosis, rheumatoid arthritis, osteoarthrosis, acne, comedos, psoriasis, tinea, onychia, paronychia, corns, callosities, alopecia and indolent tropical ulcers. The novelty of the invention lies in the ability of the said product to elicit a skin reaction at the latency-reactivation sites where the causative agent of the above-mentioned maladies resides, while bringing on no such reaction in the rest of the skin. Hitherto it has not been known, nor used, in the art that such composition of matter applied onto the skin of susceptible subjects can at first elicit pustules, papules and/or weals, then heal resulting ulcers, and that with their débriding and the removal of the necrosed tissue of the latency-reactivation sites it is feasible to eradicate the causative agent (primary stimulus, persistent antigen) from the skin, thus healing the lesions and arresting the development of these maladies at that particular stage. The said product may also prove useful in research into the above-mentioned and other maladies. The skin reaction the said product can elicit serves as an indicator of the above-mentioned maladies during their asymptomatic latent period.

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