Production and use of map kinase phosphatases and encoding...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/55 (2006.01) C07K 16/40 (2006.01) C12N 9/16 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2182967

MAP kinase phosphatases, related to CL100, dephosphorylate MAP kinase and are implicated in the control of a number of cellular pathways, including proliferation. Tumor suppressor function may be employed therapeutically. Nucleic acid encoding MAP kinase phosphatases may be used in production of the encoded polypeptides, in screening for genetic abnormality, in therapy and in obtaining further members of the family and orthologues and homologues from other species. The polypeptide may be used in raising antibodies, which themselves find use in screening for the presence of normal or aberrant polypeptide.

Cette invention se rapporte à des MAP-kinases phosphatases, apparentées à CL100, qui assurent la déphosphorylation de l'enzyme MAP-kinase et qui interviennent dans le contrôle d'un certain nombre de mécanismes cellulaires, y compris la prolifération. Leur fonction de suppression des tumeurs peut être utilisée à des fins thérapeutiques. Des acides nucléiques codant les MAP-kinases phosphatases peuvent être utilisés pour produire les polypeptides codés, pour rechercher des anomalies génétiques, pour réaliser des traitements et pour obtenir d'autres éléments de cette famille, ainsi que des orthologues et des homologues provenant d'autres espèces. Un tel polypeptide peut être utilisé pour stimuler la formation d'anticorps, qui eux-mêmes peuvent servir à rechercher la présence de polypeptides normaux ou aberrants.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Production and use of map kinase phosphatases and encoding... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Production and use of map kinase phosphatases and encoding..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production and use of map kinase phosphatases and encoding... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1986796

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.