Production and use of methionylmethionine as feed additive...

Details Production and use of methionylmethionine as feed additive... Production and use of methionylmethionine as feed additive...

A - Human Necessities

23

K

A23K 1/18 (2006.01) A23K 1/16 (2006.01) C07K 1/00 (2006.01) C07K 5/062 (2006.01)

Patent

CA 2740663

The invention relates to the use of DL-methionyl-DL-methionine and salts thereof as a feed additive in feed mixtures for animals held in aquacultures, and a method for producing DL-methionyl-DL-methionine (I) having the formula (I) by converting a urea derivative of the general formula (II) to DL-methionyl-DL-methionine, wherein the groups R1 and R2 in the urea derivatives IIa, IIb, IIc, IId, IIe, IIf, and IIg are defined as follows: IIa: R1 = COOH, R2 = NHCONH2 IIb: R1 = CONH2, R2 = NHCON- H2 IIc: R1 = CONH2, R2 = NH2 IId: R1 -R2 =-CONH- CONH-IIe: R1=CN,R2 =OH IIf:R1=CN,R2=NH2 IIg: R1= =O, R2 = H.

L'invention porte sur l'utilisation de DL-méthionyl-DL-méthionine et de ses sels, en tant qu'additif pour produits d'alimentation animale, dans des mélanges de produits d'alimentation animale destinés à des animaux élevés en aquaculture, ainsi que sur un procédé de préparation de DL-méthionyl-DL-méthionine (I) de formule (I) par transformation d'un dérivé d'urée représenté par la formule générale (II) en la DL-méthionyl-DL-méthionine, les radicaux R1 et R2 des dérivés d'urée IIa, IIb, IIc, IId, IIe, IIf et IIg étant définis comme suit : IIa : R1 = COOH, R2 = NHCONH2; IIb : R1 = CONH2, R2 = NHCONH2; IIc : R1 = CONH2, R2 = NH2; IId : R1 -R2 = -CONHCONH-; IIe : R1 = CN, R2 = OH; IIf : R1 = CN, R2 = NH2; IIg : R1= =O, R2 = H.

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