Production and use of modified cystatins

Details Production and use of modified cystatins Production and use of modified cystatins

C - Chemistry, Metallurgy

12

N

C12N 15/15 (2006.01) C07K 14/81 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2335344

Cystatins that have been modified by glycosylation in order to enhance stability and activity are disclosed, as are methods of making such cystatins and methods of using such cystatins to inhibit proteolysis.

L'invention porte sur des cystatines qui ont été modifiées par glycosylation afin d'accroître leur stabilité et leur activité. L'invention porte également sur des procédés de fabrication de ces cystatines et sur leurs procédés d'utilisation dans l'inhibition de la protéolyse.

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