Production from blood of cells of neural lineage

C - Chemistry – Metallurgy – 12 – N

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C12N 5/0797 (2010.01) A61K 35/30 (2006.01) A61P 25/00 (2006.01) C12N 5/02 (2006.01)

Patent

CA 2632836

A method including in vitro stimulating a core cell population (CCP) of at least 5 million cells that have a density of less than 1.072 g/ml, and at least 1.5% of which are CD34+CD45-/dim, to differentiate into a neural progenitor/precursor cell population (NPCP). Other embodiments are also described.

L'invention concerne un procédé qui consiste à stimuler in vitro une population de cellules centrales d'au moins 5 millions de cellules ayant une densité inférieure à 1,072 g/ml, et dont au moins 1,5 % sont CD34+CD45-/dim, pour la différenciation en population de cellules neuronales progénitrices/précurseuses. On décrit aussi d'autres variantes.

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