C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/14 (2006.01)
Patent
CA 2553237
The invention relates to a method for producing 5-chloro-N-({(5S)-2-oxo-3-[4- (3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide from 2-[(2S)-2-oxiranylmethyl]-1H-isoindol-1,3(2H)-dione, 4-(4- aminophenyl)-3-morpholinone, and 5-chlorothiophene-2-carbonyl chloride.
La présente invention concerne un procédé pour préparer du 5-chlore-<i>N</i>-({(5<i>S</i>)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phényl]-1,3-oxazolidin-5-yl}-méthyl)-2-thiophène carboxamide à partir de 2-[(2<i>S</i>)-2-oxiranylméthyl]-1<i>H</i>-isoindol-1,3(2<i>H</i>)-dione, de 4-(4-aminophényl)-3-morpholinone et de chlorure de 5-chlorthiophène-2-carbonyl.
Berwe Mathias
Grotjohann Dirk
Rehse Joachim
Thomas Christian
Bayer Healthcare Ag
Bayer Schering Pharma Aktiengesellschaft
Fetherstonhaugh & Co.
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