C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 65/01 (2006.01) C07C 51/00 (2006.01) C07C 51/09 (2006.01) C07C 51/36 (2006.01) C07C 67/303 (2006.01) C07C 67/343 (2006.01) C07C 69/732 (2006.01)
Patent
CA 2361156
The present invention relates to production of 2- cyclohexyl-2-hydroxy-2-phenylacetic acid useful as an intermediate for pharmaceutical products, by an industrial means, economically, safely in a good yield. Novel 2-(2'- cyclohexen-1'-yl)-2-hydroxy-2-phenylacetic acid ester obtained by reacting cyclohexene and benzoylformic acid ester in the presence of a Lewis acid is hydrolyzed and reduced to give 2- cyclohexyl-2-hydroxy-2-phenylacetic acid.
Gao Wei-Guo
Igi Masami
Ikemoto Tetsuya
Takeda Mitsuhiro
Fetherstonhaugh & Co.
Sumika Fine Chemicals Co. Ltd.
Sumitomo Chemical Company Limited
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