Production method of capsinoid by dehydrating condensation,...

C - Chemistry – Metallurgy – 07 – C

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C07C 67/08 (2006.01) C07C 67/62 (2006.01) C07C 69/28 (2006.01)

Patent

CA 2598415

In the production methods of capsinoid by esterification using an enzyme, a method of conveniently obtaining capsinoid in a high yield in a short time without using a dehydrating agent is provided. In addition, a method of stable preservation of produced capsinoid by purifying the obtained capsinoid under stable conditions is provided. A fatty acid represented by the formula (1) and a hydroxymethylphenol represented by the formula (2) are condensed without solvent or in a low-polar solvent, using an enzyme as a catalyst to give an ester compound represented by the formula (3). In addition, a fatty acid represented by the formula (4) is added to the ester compound represented by the formula (3) for stabilization. wherein each symbol is as defined in the specification.

Dans le contexte de la production d'un capsinoïde par estérification au moyen d'un enzyme, l'invention concerne un procédé simple d'obtention de capsinoïdes, rapidement et à fort rendement, sans utilisation d'agent hydratant. Est également décrit un procédé de conservation stable du capsinoïde ainsi obtenu par purification en conditions de stabilité. Un acide gras représenté par la formule (1) et un hydroxyméthylphénol représenté par la formule (2) sont condensés sans solvant ou dans un solvant faiblement polaire au moyen d'un enzyme utilisé comme catalyseur pour donner le jour à un composé ester de formule (3). De plus, à des fins de stabilisation, on ajoute un acide gras représenté par la formule (4) au composé ester de formule (3). Chaque symbole est comme défini dans le descriptif.

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