Production method of nicotine transdermal preparation

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/70 (2006.01) A61K 31/465 (2006.01) A61M 37/00 (2006.01) A61P 25/34 (2006.01)

Patent

CA 2554728

The present invention provides a production method of a nicotine transdermal preparation, which includes a step of forming, on a support, an adhesive layer containing an adhesive and a liquid ingredient compatible with the adhesive, and a step of impregnating the adhesive layer with nicotine by continuously applying nicotine to the adhesive layer. The production method of the present invention permits direct application of nicotine to the adhesive layer, which is not possible by conventional techniques, and the nicotine transdermal preparation provided by the method is associated with less physical skin irritation on peeling off and affords a good feeling during adhesion.

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