Production of 1,4-dihydroquinoline-3-carboxylic acid...

C - Chemistry – Metallurgy – 07 – D

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260/246.2, 260/2

C07D 215/56 (2006.01) C07D 401/04 (2006.01) C07D 413/04 (2006.01)

Patent

CA 1175836

ABSTRACT OF THE DISCLOSURE New 7-dialkylamino-1-substituted-6-halogeno-4-oxo- 1,4-dihydroquinoline-3 carboxylic acids of the formula: Image (I) and non-toxic pharmaceutically acceptable acid addition salts thereof are prepared by condensing a secondary amine of the formula: Image (II) with a 1-substituted-6-halogeno-7-chloro-4-oxo-1,4-dihydro- quinoline-3-carboxylic acid of the formula: Image (III) The products have antibacterial properties.

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