Production of 5-methyl-n-aryl-2-pyrrolidone and...

Details Production of 5-methyl-n-aryl-2-pyrrolidone and... Production of 5-methyl-n-aryl-2-pyrrolidone and...

A - Human Necessities

01

N

A01N 43/36 (2006.01) A61K 31/4015 (2006.01) C07D 207/12 (2006.01)

Patent

CA 2520304

This invention relates to a process for producing 5-methyl-N-aryl-2- pyrrolidone, 5-methyl-N-alkyl-2-pyrrolidone, and 5-methyl-N-cycloalkyl-2- pyrrolidone by reductive amination of levulinic acid esters with aryl or alkyl amines utilizing a metal catalyst, which is optionally supported.

L'invention concerne un procédé de production de 5-méthyl-N-aryl-2-pyrrolidone, de 5-méthyl-N-alkyl-2-pyrrolidone, et de 5-méthyl-N-cycloalkyl-2-pyrrolidone par amination réductrice d'esters d'acide lévulinique avec des arylamines ou des alkylamines au moyen d'un catalyseur métallique éventuellement supporté.

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