Production of 5-methyl-n-aryl-2-pyrrolidone and...

Details Production of 5-methyl-n-aryl-2-pyrrolidone and... Production of 5-methyl-n-aryl-2-pyrrolidone and...

A - Human Necessities

61

K

A61K 31/401 (2006.01) C07D 207/04 (2006.01)

Patent

CA 2520425

This invention relates to a process for producing 5-methyl-N-aryl-2- pyrrolidone and 5-methyl-N-cycloalkyl-2-pyrrolidone by reductive amination of levulinic acid or its derivatives with aryl amines, ammonia or ammonium hydroxide utilizing a metal catalyst, which is optionally supported.

L'invention concerne un procédé de production de 5-méthyl-N-aryl-2-pyrrolidone et de 5-méthyl-N-cycloalkyl-2-pyrrolidone par amination réductrice d'acide lévulinique ou de ses dérivés avec des arylamines, de l'ammoniaque ou de l'hydroxyde d'ammonium, faisant appel à un catalyseur métallique, se trouvant éventuellement sur un support.

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