Production of 5-methyl-n-(methyl aryl)-2-pyrrolidone,...

Details Production of 5-methyl-n-(methyl aryl)-2-pyrrolidone,... Production of 5-methyl-n-(methyl aryl)-2-pyrrolidone,...

A - Human Necessities

61

K

A61K 31/4015 (2006.01) A01N 43/36 (2006.01) C07D 207/12 (2006.01)

Patent

CA 2520431

This invention relates to a process for producing 5-methyl-N-(methyl aryl)-2- pyrrolidone, 5-methyl-N-(methyl cycloalkyl)-2-pyrrolidone and 5-methyl-N-alkyl- 2-pyrrolidone by reductive amination of levulinic acid with aryl cyano compounds utilizing a metal catalyst, which is optionally supported.

L'invention concerne un procédé de production de 5-méthyl-N-(méthylaryl)-2-pyrrolidone, de 5-méthyl-N-(méthylcycloalkyl)-2-pyrrolidone et de 5-méthyl-N-alkyl-2-pyrrolidone par amination réductrice d'acide lévulinique avec des composés cyano au moyen d'un catalyseur métallique éventuellement supporté.

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