Production of alkaloid dimers using ferric ion

Details Production of alkaloid dimers using ferric ion Production of alkaloid dimers using ferric ion

C - Chemistry, Metallurgy

07

D

260/237.3

C07D 519/04 (2006.01)

Patent

CA 1303036

ABSTRACT OF THE DISCLOSURE Alkaloid dimers are formed by coupling vindoline and catharanthine in the presence of ferric ion. The predominant products are 3',4'-anhydrovinblastine and vinblastine when reaction conditions are selected appropriately.

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