Production of amino sugars

Details Production of amino sugars Production of amino sugars

C - Chemistry, Metallurgy

12

N

C12N 1/19 (2006.01) C12P 19/28 (2006.01) C12N 9/10 (2006.01) C12N 9/14 (2006.01) C12N 15/54 (2006.01)

Patent

CA 2546914

The present invention provides a method for producing an amino sugar selected from the group consisting of N-acetylglucosamine, glucosamine, or a combination thereof. The method comprises culturing a yeast in a culture medium and recovering N-acetylglucosamine, glucosamine, or a combination thereof, wherein the yeast comprises an exogenous nucleic acid sequence encoding glucosamine-6-phosphate synthase operably linked to a promoter. The invention also provides a genetically modified yeast that produces an amino sugar selected from the group consisting of N-acetylglucosamine, glucosamine, or a combination thereof.

L'invention porte sur un procédé de production d'un sucre amino (une N-acétylglucosamine, une glucosamine ou leur combinaison), consistant à cultiver une levure dans un milieu de culture puis à récupérer la N-acétylglucosamine, la glucosamine ou leur combinaison. ladite levure comporte une séquence exogène d'acides nucléiques codant pour la glucosamine-6-phosphate synthase, fonctionnellement liée à un promoteur: L'invention porte également sur une levure génétiquement modifiée produisant un sucre amino sélectionné parmi une N-acétylglucosamine, une glucosamine ou leur combinaison.

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