C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C12P 21/02 (2006.01) A61K 38/16 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2670014
The present application provides methods of producing antimicrobial peptides (AMPs) in a cell, for example by expression a fusion protein that includes small ubiquitin related modifier (SUMO) and an AMP in the cell. Also provided are nucleic acid and protein sequences of SUMO-AMP fusion proteins, and kits that include such molecules.
La présente invention concerne des procédés de fabrication de peptides anti-microbiens (AMP) dans une cellule, par exemple, par l'expression d'une protéine de fusion qui comprend un petit modificateur apparenté à l'ubiquitine (SUMO) et un AMP dans la cellule. L'invention concerne également des séquences d'acide nucléique et protéiques de protéines de fusion SUMO-AMP, et des coffrets qui comprennent des telles molécules.
Bommarius Bettina
Cheng Xiaodong
Kalman Daniel
Sherman Melanie
Bommarius Bettina
Cheng Xiaodong
Emory University
Kalman Daniel
Sherman Melanie
LandOfFree
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