Production of biologically active forms of csf using a...

Details Production of biologically active forms of csf using a... Production of biologically active forms of csf using a...

C - Chemistry, Metallurgy

12

N

195/1.14, 195/1.

C12N 15/86 (2006.01) C07K 14/535 (2006.01) C12N 15/27 (2006.01) C12N 15/866 (2006.01)

Patent

CA 1317244

Abstract of the Disclosure The expression of biologically active CSFs in insect cells (Spodoptera frugiperda) is disclosed. Numerous forms of CSF-1 are expressed and secreted as biologically active dimers. DNA transfer vectors and expression vectors that encode forms of CSF-1 and allow for their expression are disclosed and claimed. G-CSF is additionally expressed in insect cells in active form. DNA transfer vectors and expression vectors that encode G-CSF are disclosed and claimed.

572544

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