Production of chimeric mouse-human antibodies with...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 16/00 (2006.01) C07K 16/46 (2006.01) C07K 17/00 (2006.01) C12N 15/63 (2006.01) G01N 33/531 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1341351

Gene expression elements and their use in production of chimeric antibodies with human constant regions and murine variable regions, and mouse human chimeric antibodies having specificity to human tumor cells, methods of their production, and their use.

610388

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