Production of collagen in the milk of transgenic mammals

Details Production of collagen in the milk of transgenic mammals Production of collagen in the milk of transgenic mammals

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A23C 9/00 (2006.01) A23C 9/20 (2006.01) A23J 1/20 (2006.01) A23J 3/06 (2006.01) C07K 14/78 (2006.01) C12N 15/53 (2006.01) C12N 15/85 (2006.01) C12P 21/06 (2006.01)

Patent

CA 2195970

The invention provides transgenic nonhuman mammals capable secreting exogenous procollagen or collagen into their milk. The mammals are healthy and capable of producing procollagen or collagen at high levels, usually in trimeric form. Suitable transgenes for incorporation into the mammals are also provided.

La présente invention concerne des mammifères transgéniques non humains capables de sécréter du procollagène ou du collagène exogène dans leur lait. Ces mammifères sont en bonne santé et capables de produire des niveaux élevés de procollagène ou de collagène, habituellement sous forme trimère. On divulgue également des transgènes pouvant être incorporés à ces mammifères.

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