Production of cyanide hydratase

Details Production of cyanide hydratase Production of cyanide hydratase

C - Chemistry, Metallurgy

12

N

362/12, 195/123,

C12N 9/88 (2006.01) C02F 3/00 (2006.01) C02F 3/12 (2006.01) C02F 3/34 (2006.01)

Patent

CA 1321967

B 33774 Abstract Production of cyanide hydratase A process for the production of the enzyme cyanide hydratase which comprises continuously cultivating a microorganism strain under specified conditions of temperature, pH and dilution rate whilst continuously supplying cyanide ions and/or hydrogen cyanide and/or compounds which generate cyanide ions and/or hydrogen cyanide under fermentation conditions to the culture. A method for the treatment of a cyanide-containing material to degrade the cyanide therein which uses cyanide hydratase produced by the process of the invention is also claimed. Preferably the microorganism is a Fusarium strain, in particular Fusarium lateritium Naas CMI 300533 deposited at The Commonwealth Mycological institute, Kew, Richmond, Surrey, England under the terms of the Budapest Treaty.

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