Production of d-.alpha.-aminocarboxylic acids by the...

C - Chemistry – Metallurgy – 12 – P

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C12P 13/04 (2006.01) C12P 41/00 (2006.01)

Patent

CA 2017939

ABSTRACT OF THE DISCLOSURE In the production of D-.alpha.-aminocarboxylic acids by the biotransformation of hydantoins that are monosubstituted in the fifth position in an aqueous medium in the presence of cells of the microorganism Agrobacterium radiobacter, an increase in the space-time yield is achieved if the biotransformation is effected in an overpressure at the start of the reaction. A further improvement results if this overpressure is maintained for a period of at least 16 hours, after which the reaction vessel is depressurized and the biotransformation continued at atmospheric pressure.

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