Production of fluormethyl...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 41/09 (2006.01) C01B 7/19 (2006.01) C07C 41/38 (2006.01) C07C 41/42 (2006.01) B01D 3/00 (2006.01) C07C 43/12 (2006.01)

Patent

CA 2403105

An improved process for preparing fluromethyl 2,2,2-trifluoro-1- (trifluoromethyl)ethyl ether (sevoflurane) by reacting 1,1,1,3,3,3-hexafluoro-2-propanol with formaldhyde and hydrogen fluoride either A) under distillation conditions or B) in the presence of or with the subsequent addition of a solvent capable of selectively extracting sevoflurane.

La présente invention concerne un procédé amélioré de production d'éther de fluorométhyl 2,2,2-trifluoro-1-(trifluorométhyl)éthyle (ou, sevoflurane), consistant à mettre à réagir 1,1,1,3,3,3-hexafluoro-2-propanole avec du formaldéhyde et du fluorure d'hydrogène, soit A) dans des conditions de distillation, soit B) en présence/addition ultérieure d'un solvant capable d'extraire le sevoflurane de manière sélective.

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