Production of furanones

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 307/58 (2006.01) A01N 43/08 (2006.01) A61K 31/34 (2006.01) C08F 20/00 (2006.01) C08F 24/00 (2006.01) C08F 224/00 (2006.01) C23F 14/02 (2006.01) C23F 15/00 (2006.01)

Patent

CA 2328364

The present invention relates to the side chain functionalisation of fimbrolides (halogenated 3-alkyl-5-methylene-2(5H)-furanones) and their synthetic analogues, that yields fimbrolides substituted with a halogen, an oxygen or a nitrogen functionality in the alkyl chain, especially fimbrolide alcohols, carboxylate and sulfinate and sulfonate esters, ethers, aldehydes, ketones, acids, amides, nitro derivatives, hydrophobic, hydrophilic and fluorophilic alkyl derivatives and polymers.

L'invention porte sur la fonctionnalisation des chaînes latérales des fimbrolides (3-alkyl-5-méthylène-2[5H]-furanones halogénées) et de leurs analogues de synthèse, qui donne des fimbrolides substitués par une fonctionnalité halogène, oxygène ou azote dans la chaîne alkyle, et en particulier: des alcools fimbrolidiques; des esters carboxylates, sulfinates, sulfonates; des éthers; des aldéhydes; des cétones; des acides; des amides; des dérivés nitro; des dérivés alkyliques, hydrophobes, hydrophiles et fluorophiles; et des polymères.

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