Production of herpes simplex viral proteins

Details Production of herpes simplex viral proteins Production of herpes simplex viral proteins

C - Chemistry, Metallurgy

12

N

530/13, 195/1.2,

C12N 15/38 (2006.01) C07H 21/04 (2006.01) C07K 14/035 (2006.01) C12N 15/70 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1295561

ABSTRACT OF THE DISCLOSURE Methods and compositions are provided for the cloning and expression of Herpes Simplex Virus (HSV type 1 or type 2) glycoprotein (gD) gene in single-cell host organisms. Also described are methods for culturing these novel single-cell organisms to produce HSV-gene products. The HSV gD- related polypeptides produced by the recombinant DNA techniques described herein may be formulated for use as immunogens in vaccines to protect against HSV-1 and HSV-2 infections.

432633

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