C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/00 (2006.01) A61K 35/12 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) C12N 15/86 (2006.01) C12N 15/867 (2006.01)
Patent
CA 2156725
A method for producing high-titer, helper-free infectious retroviruses is disclosed which employs a novel strategy that uses transient transfection of new retroviral producer cell lines, ecotropic line BOSC 23 and amphotropic line CAK 8, both of which cell lines and their precursor cell lines are disclosed. Because of the advantages over stable packaging cell lines, the BOSC 23 and CAK 8 transient transfection systems greatly facilitate and extend the use of helper-free retroviral vectors. The cell lines and corresponding methods possess wide application in both the medical and biotechnical fields, including gene therapy. These potential applications are disclosed and illustrated.
Baltimore David
Nolan Garry P.
Pear Warren S.
Scott Martin L.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Rockefeller University (the)
LandOfFree
Production of high titer helper-free retroviruses by... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Production of high titer helper-free retroviruses by..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of high titer helper-free retroviruses by... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1658140