Production of human lysozyme

Details Production of human lysozyme Production of human lysozyme

C - Chemistry, Metallurgy

12

N

195/1.2, 195/1.2

C12N 15/56 (2006.01) C12N 1/19 (2006.01) C12N 9/36 (2006.01) C12N 15/81 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1305439

PRODUCTION OF HUMAN LYSOZYME Abstract of the Disclosure A DNA sequence wherein a DNA segment coding for a signal peptide of the formula: M-R-S-F-L-L-L-A-L-C-F-L-P-L-A-A-L G is bound to the 5' end of a DNA segment coding for human lysozyme, a cell transformed with the above DNA sequence and a process for producing human lysozyme, which comprises cultivating the above cell accumulating human lysozyme in the culture and recovering the same are disclosed. The above techniques make the mass production of human lysozyme useful as phermaceuticals possible. The present signal peptide is superior to that of hen egg white lysozyme for secretive production of human lysozyme.

540790

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