Production of immunogens by antigen conjugation to liposomes

A - Human Necessities – 61 – K

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167/129, 167/45

A61K 39/385 (2006.01) A61K 9/127 (2006.01) A61K 39/39 (2006.01)

Patent

CA 1243946

ABSTRACT The invention disclosed relates to antigen/liposome conjugates, wherein the antigen is covalently bound to lipid molecules in the surface membrane of liposome vesicles, and wherein at least about 25 g of antigen is provided per mole of lipid. Enhanced immunogenicity is achieved by injecting the antigen/liposome conjugate so formed into an appropriate vertebrate host to produce antibodies.

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