Production of immunoproximity catalysts

Details Production of immunoproximity catalysts Production of immunoproximity catalysts

C - Chemistry, Metallurgy

07

K

167/139, 195/33

C07K 16/44 (2006.01) C12N 9/00 (2006.01)

Patent

CA 1340534

The invention relates to novel immunoproximity catalysts. The catalysts are derived from antibody molecules. The process includes selecting a hapten based on its relationship to the structure of a transition state complex of the selected reaction so that the hapten, upon attachment to a carrier protein and injection into an animal, elicits an immune response in which the desired antibody is produced. This antibody is modified by the specific, covalent attachment of the catalytic group involved in the selected reaction, yielding an immunoproximity catalyst which is a substrate-specific, antibody catalyst.

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