Production of l-amino acids by transamination

Details Production of l-amino acids by transamination Production of l-amino acids by transamination

C - Chemistry, Metallurgy

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C12P 13/04 (2006.01) C12N 9/10 (2006.01) C12N 11/18 (2006.01) C12P 13/06 (2006.01) C12P 13/08 (2006.01) C12P 13/12 (2006.01) C12P 13/22 (2006.01) C12P 41/00 (2006.01)

Patent

CA 1248898

ABSTRACT OF THE DISCLOSURE A process is described for producing alpha amino acids or derivatives thereof. The process comprises reacting an alpha-keto acid with L-aspartic acid in the presence of transaminase enzyme to produce (1) an alpha amino acid corresponding to said alpha-keto acid and (2) oxaloacetate; and decarboxylating said oxaloacetate. Also described is a process for producing L-amino acids directly from the corresponding D,L-amino acid racemic mixture. The process comprises reacting said D,L-amino acid mixture in admixture with a D-amino acid oxidase and a transaminase in the presence of a suitable amino group donor.

462306

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